phenobarbital sodium contraindications for Dummies

phenobarbital sodium contraindications for Dummies

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pentobarbital will minimize the extent or effect of ziprasidone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Mysterious.

pentobarbital will decrease the level or effect of quinine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unidentified.

pentobarbital boosts toxicity of methoxyflurane by raising metabolism. Contraindicated. Elevated metabolism of methoxyflurane to nephrotoxic compounds.

pentobarbital will reduce the level or effect of diltiazem by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.

Contraindicated (1)pentobarbital will minimize the extent or effect of cobimetinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Avoid coadministration. Sturdy or average CYP3A inducers may reduce cobimetinib systemic exposure by >80% and minimize its efficacy.

pentobarbital will lessen the extent or effect of pantoprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unfamiliar.

pentobarbital will reduce the level or effect of diazepam buccal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor. Solid or average CYP3A4 inducers might enhance level of diazepam elimination; for that reason, efficacy of diazepam might be lowered.

Keep track of Closely (one)pentobarbital will reduce the extent or effect of levamlodipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.

pentobarbital will lessen the level or effect of montelukast by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Mysterious.

pentobarbital will lower the level or effect of tamoxifen by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

pentobarbital will decrease the level or effect of irinotecan liposomal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.

Abrupt cessation immediately after prolonged use inside the dependent particular person could lead to withdrawal symptoms, such as delirium, convulsions, And maybe Loss of life. Barbiturates needs to be withdrawn progressively from any affected person known to generally be getting excessive dosage over extensive periods of time. (See “Drug Abuse and Dependence” section.)

pentobarbital will reduce the extent or effect of bosentan by influencing hepatic enzyme CYP2C9/ten metabolism. Slight/Significance Not known.

pentobarbital will minimize more info the level or effect of alfuzosin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Mysterious.